Target Product Profile (TPP)

What is a Target Product Profile (TPP)?
A target product profile refers to what the expected properties of a drug will be once development (ie studies) are complete. It usually consists of many elements including information on expected dosing, route of administration, potential efficacy and safety profile, etc. As new data emerge once studies readout the TPP is generally updated to reflect the latest knowledge.

The TPP is an important strategic tool used within pharma companies to plan for and assess investigational agents including the market potential, potential marketing strategies, etc. It is also important to levelset between various functions and can serve as a potential base case to compare actual results against. Finally, TPPs can be shared with regulatory authorities in earlier discussions as study design and other decisions are being talked through and made.